A Brief Look at Refractory Celiac Disease – Gastrointestinal Diseases

Based in Sydney, Australia, Nick Catsaras is an accomplished executive who has spearheaded operations at several healthcare ventures. Since 2010, he has served as managing director at Pegasus Research, PL, where he focuses on areas involving computer programming, statistical analysis, and data mining. Nick Catsaras’ medical interests include gastrointestinal disease.

Celiac disease can cause gastrointestinal bleeding, poor nutrient absorption, bowel obstruction, weight loss, and anemia, among other symptoms. People with celiac disease are medically required to abstain from ingesting gluten, which triggers a destructive immune system reaction. For most people, formulating and strictly following a gluten-free diet plan helps manage symptoms.

Refractory celiac disease is a type of celiac disease that does not improve with gluten-free diets. If a person experiences symptoms of celiac disease after abstaining from gluten for at least 12 months, they suffer from refractory celiac disease. Doctors treat refractory celiac disease with immunosuppressants (such as steroids and methotrexate), chemotherapy, and stem cell therapy.

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