Applying more than 30 years of experience in information technology and finance, Dr. Nick Catsaras handles the data mining and algorithmic data analysis at Pegasus Research PL, a firm based in Sydney, Australia, where he serves as managing director. A medical doctor, Dr. Nick Catsaras stays well-informed with ongoing research efforts, particularly on gastrointestinal diseases.
Scientists from the Translational Research Institute (TRI) Australia conducted a study of mice at The University of Queensland Diamantina Institute to find out how growth hormones can aid in liver regeneration. The study has found out that the lack of the receptor necessary for transmitting growth hormones to the cells caused the death of mice after surgically removing two-thirds of their liver. It was also observed that mice with normal growth hormone receptors were able to survive after the surgery.
The researchers have found out that growth hormones induce the production of HLA-G, a protein that suppresses inflammation after surgery. Mice that received HLA-G experienced reduced inflammation, which led to liver regeneration.
This study highlights the important role HLA-G plays in increasing the survivability of those who have undergone liver surgery, particularly in liver transplant patients. The researchers look forward to future explorations of growth hormones as therapy for patients who have undergone an organ transplant.
Nick Catsaras 